UPF0568 Protein C14orf166 (RTRAF) (AA 1-244) antibody

Catalog No. ABIN7599147

This anti- antibody is a Rabbit Polyclonal antibody detecting in ELISA, IHC, WB, IF and ICC. Suitable for Human, Mouse and Rat.

Quick Overview for UPF0568 Protein C14orf166 (RTRAF) (AA 1-244) antibody (ABIN7599147)

Target: UPF0568 Protein C14orf166 (RTRAF)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details

Binding Specificity: AA 1-244

Purpose: Anti-C14orf166/RTRAF Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-C14orf166/RTRAF Antibody Picoband® (ABIN7599147). Tested in WB, IHC, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human C14orf166/RTRAF recombinant protein (Position: M1-R244). Human C14orf166/RTRAF shares 97.1% amino acid (aa) sequence identity with mouse C14orf166/RTRAF.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL
1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/18/2014. 2. Howng, S.-L., Hsu, H.-C., Cheng, T.-S., Lee, Y.-L., Chang, L.-K., Lu, P.-J., Hong, Y.-R. A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3-beta and is highly expressed in brain tumors. FEBS Lett. 566: 162-168, 2004. 3. Huarte, M., Sanz-Ezquerro, J. J., Roncal, F., Ortin, J., Nieto, A. PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators. J. Virol. 75: 8597-8604, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: UPF0568 Protein C14orf166 (RTRAF)

Alternative Name: RTRAF

Background:

Synonyms: RTRAF, C14orf166, CGI-99, RNA transcription, translation and transport factor protein, CLE7 homolog, CLE, hCLE

Background: Enables RNA binding activity, RNA polymerase II complex binding activity, and identical protein binding activity. Involved in negative regulation of protein kinase activity, positive regulation of transcription by RNA polymerase II, and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton, nucleoplasm, and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex.

Molecular Weight: 28 kDa

Gene ID: 51637

UniProt: Q9Y224